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  发表文章: 

  [1] Zhu B, Wang J-R, Zhang Q, Mei X. Greener solid-state synthesis: stereo-selective [2 + 2] photodimerization of vitamin K3 controlled by halogen bonding. CrystEngComm 2016;18:6327-30. 

  [2] Zhang Q, Mei X. Two New Polymorphs of Huperzine A Obtained from Different Dehydration Processes of One Monohydrate. Cryst Growth Des 2016;16:3535-42. 

  [3] Wang J-R, Fan X, Ding Q, Mei X. Determination of absolute configuration using heavy atom based co-crystallization method: Halogen atom effects. J Mol Struct 2016;1119:269-75. 

  [4] Wang J-R, Wang X, Yang Y, Chen X, Mei X. Solid-state characterization of 17beta-estradiol co-crystals presenting improved dissolution and bioavailability. CrystEngComm 2016;18:3498-505. 

  [5] He H, Huang Y, Zhang Q, Wang J-R, Mei X. Zwitterionic Cocrystals of Flavonoids and Proline: Solid-State Characterization, Pharmaceutical Properties, and Pharmacokinetic Performance. Cryst Growth Des 2016;16:2348-56. 

  [6] Huang Y, Zhang Q, Wang J-R, Lin K-L, Mei X. Amino acids as co-amorphous excipients for tackling the poor aqueous solubility of valsartan. Pharm Dev Technol 2016:1-8. 

  [7] Zhu B, Wang J-R, Zhang Q, Mei X. Improving Dissolution and Photostability of Vitamin K3 via Cocrystallization with Naphthoic Acids and Sulfamerazine. Cryst Growth Des 2016;16:483-92. 

  [8] Zhang Q, Jiang L, Mei X. Thermodynamic and kinetic investigation of agomelatine polymorph transformation. Pharm Dev Technol 2016;21:196-203. 

  [9] Wang J-R, Yu Q, Dai W, Mei X. Drug-drug co-crystallization presents a new opportunity for the development of stable vitamins. Chem Commun 2016;52:3572-5. 

  [10] Wang J-R, Zhu B, Yu Q, Mei X. Selective crystallization of vitamin D3 for the preparation of novel conformational polymorphs with distinctive chemical stability. CrystEngComm 2016;18:1101-4. 

  [11] Zhang Q, Li M, Mei X. A new polymorph of 1-hydroxy-2-naphthoic acid obtained during failed co-crystallization experiments. Acta Cryst B 2015;71:119-21. 

  [12] Zhu B, Wang J-R, Mei X. Insight into the Phase Transformation among Various Solid Forms of Baicalein. Cryst Growth Des 2015;15:4959-68. 

  [13] He H, Jiang L, Zhang Q, Huang Y, Wang J-R, Mei X. Polymorphism observed in dapsone-flavone cocrystals that present pronounced differences in solubility and stability. CrystEngComm 2015;17:6566-74. 

  [14] Jia L, Zhang Q, Wang J-R, Mei X. Versatile solid modifications of icariin: structure, properties and form transformation. CrystEngComm 2015;17:7500-9. 

  [15] Wang JR, Yu X, Zhou C, Lin Y, Chen C, Pan G, et al. Improving the dissolution and bioavailability of 6-mercaptopurine via co-crystallization with isonicotinamide. Bioorg Med Chem Lett 2015;25:1036-9. 

  [16] Wang JR, Li S, Zhu B, Mei X. Insight into the conformational polymorph transformation of a block-buster multiple sclerosis drug fingolimod hydrochloride (FTY 720). J Pharm Biomed Anal 2015;109:45-51. 

  [17] Wang J-R, Ye C, Zhu B, Zhou C, Mei X. Pharmaceutical cocrystals of the anti-tuberculosis drug pyrazinamide with dicarboxylic and tricarboxylic acids. CrystEngComm 2015;17:747-52. 

  [18] Xu Y, Jiang L, Huang Y, Wang JR, Mei X. Solid-state characterization and transformation of various creatine phosphate sodium hydrates. J Pharm Sci 2014;103:3688-95. 

  [19] Xu Y, Jiang L, Mei X. Supramolecular structures and physicochemical properties of norfloxacin salts. Acta Cryst B 2014;70:750-60. 

  [20] Jiang L, Huang Y, Zhang Q, He H, Xu Y, Mei X. Preparation and Solid-State Characterization of Dapsone Drug–Drug Co-Crystals. Cryst Growth Des 2014;14:4562-73. 

  [21] Wang X, Zhang Q, Jiang L, Xu Y, Mei X. Isostructurality in six celecoxib co-crystals introduced by solvent inclusion. CrystEngComm 2014;16:10959-68. 

  [22] Wang J-R, Ye C, Mei X. Structural and physicochemical aspects of hydrochlorothiazide co-crystals. CrystEngComm 2014;16:6996. 

  [23] Zhang Q, Lu L, Dai W, Mei X. Polymorphism and isomorphism of Huperzine A solvates: structure, properties and form transformation. CrystEngComm 2014;16:1919. 

  [24] Wang JR, Zhou C, Yu X, Mei X. Stabilizing vitamin D(3) by conformationally selective co-crystallization. Chem Commun 2014;50:855-8. 

  [25] Zhang Q, Lu L, Dai W, Mei X. New Polymorphs of Huperzine A: Preparation, Structures, and Physicochemical Properties of Anhydrous Crystal Forms. Cryst Growth Des 2013;13:2198-207. 

  [26] Wang J-R, Wang X, Lu L, Mei X. Highly Crystalline Forms of Valsartan with Superior Physicochemical Stability. Cryst Growth Des 2013;13:3261-9. 

    

  授权专利: 

  [1] 梅雪锋, 章海燕, 张奇, 陆骊烨, 戴文娟. 石杉碱甲多晶型体、其制备方法、包含所述多晶型体的药物组合物及其用途. 专利号:ZL 201210078474.9. 

  [2] 梅雪锋, 王建荣. 缬沙坦的多晶型及其制备方法. 专利号:ZL 201210038785.2. 

  [3] 梅雪锋, 王建荣, 许聪慧. 芬戈莫德粘酸盐及其晶体的制备方法和用途. 专利号:ZL 201210326164.4. 

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